Computer algorithms for checking and predicting the acyclovir-resistance of herpes simplex and varicello viruses on the molecular level of the thymidine kinase

For HSV1 TK acyclovir-resistance checking one can download:

HSV1TKphylo eng.xls

For HSV2 TK acyclovir-resistance checking one can download:

HSV2TKphylo eng.xls

For VZV TK acyclovir-resistance checking one can download:

VZVTKphylo.xls

For publication of the results you should cite these two abstracts:

1. Khrustalev V.V., Barkovsky E.V., Zadorozniy D.Y. Computer algorithms for checking and predicting the acyclovir-resistance of herpes simplex viruses on the molecular level of the thymidine kinase. Acta Biochimica Polonica. 2008. Vol.55. Supplement 4. P.67.
2. Khrustalev V.V., Barkovsky E.V., Zadorozniy D.Y. Genotypic method for checking and predicting acyclovir-resistance on the level of human alphaherpesviruses thymidine kinases. FEBS Journal. 2009. Vol.276. Supplement 1. P.317.

You can simply paste your nucleotide sequence of thymidine kinase into the special cell on "sequence2" list and see the answer on the "RESULT" list.

For the further development of our algorithms we have made special “information” list where one can find all necessary data about types of observed mutations.

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