RUS   ENG           

Ãëàâû â êîëëåêòèâíûõ ìîíîãðàôèÿõ

 

  1. Khrustalev V.V., Barkovsky E.V. Bioinformatical approaches for studies on replication-associated and transcription-associated mutational pressure, interpretations and applications // Advances in Genetics Research (Nova Science Publishers, Inc., New York) - 2011. - Vol.6. - P.1-108.


 

Ñòðàíèöû íà ñàéòå ðåñóðñà SciTopics

 

  1. Khrustalev V.V., Barkovsky E.V. Original computer algorithms for studies on directional mutational pressure // SciTopics – 2011.

  2. Khrustalev V.V., Barkovsky E.V. Numerous consequences of the directional mutational pressure // SciTopics – 2010.


 

Ñòàòüè, äîñòóïíûå áåñïëàòíî

 

  1. Khrustalev V.V., Lelevich S.V., Barkovsky E.V. Zebra Finch glucokinase containing two homologous halves is an in silico chimera // ISRN Computational Biology. – 2013. – Vol.2013. – N. 790240. – P. 1 – 6.

  2. Lelevich S. V., Khrustalev V.V., Barkovsky E.V. Inhibition of rat muscle and liver phosphofructokinases by high doses of ethanol // Biochemistry Research International. – 2013. – Vol.2013. – N. 495135. – P. 1 – 8.

  3. Lelevich S.V., Khrustalev V.V., Barkovsky E.V., Shedogubova T.A. The influence of ethanol on pyruvate kinases activity in vivo, in vitro, in silico // American Journal of Medical and Biological Research. – 2013. – Vol.1. – No.1. – P. 6-15.

  4. Khrustalev V.V., Barkovsky E.V. In silico directed mutagenesis using software for glycosylation sites prediction as a new step in antigen design // Journal of Integrated OMICS.– 2012. – Vol.2. – Issue 1. – P.31-36.

  5. Khrustalev V.V., Barkovsky E.V., Vasilevskaya A.E., Skripko S.M., Kolodkina V.L., Ignatyev G.M., Semizon P.A. A method for estimation of immunogenic determinants mutability: case studies of HIV1 gp120 and diphtheria toxin // Journal of Integrated OMICS.– 2011. – Vol.1. – Issue 2. – P.236-252.

  6. Khrustalev V.V. HIV1 V3 loop hypermutability is enhanced by the guanine usage bias in the part of env gene coding for it // In Silico Biology. – 2009. – Vol.9. – Number 4. – P.255-269. (Electronic version: Vol.9. – ¹0022).

  7.  Khrustalev V.V., Barkovsky E.V. Main Pathways of Proteome Simplification in Alphaherpesviruses Under the Influence of the Strong Mutational GC-pressure // Journal of Proteomics and Bioinformatics – 2009. – Vol. 2. – Issue 2. – P.88-96.

 


 

Ñòàòüè

 

  1. Khrustalev V.V., Khrustaleva T.A., Barkovsky E.V. Random coil structures in bacterial proteins. Relationships of their amino acid compositions to flanking structures and corresponding genic base compositions // Biochimie – 2013. – Vol.95. – Issue 9. – P. 1745-1754.

  2. Khrustalev V.V., Ghaznavi-Rad E., Neela V., Shamsudin M., Amouzandeh-Nobaveh A., Barkovsky E.V. Short repeats in the spa gene of Staphylococcus aureus are prone to nonsense mutations: stop codons can be found in strains isolated from patients with generalized infection // Research in Microbiology – 2013. – Vol.164. – Issue 9. – P. 913–922.

  3. Khrustalev V.V., Barkovsky E.V. Stabilization of secondary structure elements by specific combinations of hydrophilic and hydrophobic amino acid residues is more important for proteins encoded by GC-poor genes  // Biochimie - 2012. - Vol.94. - P. 2706-2715.

  4. Khrustalev V.V., Arjomanzadegan M., Barkovsky E.V., Titov L.P. Low rates of synonymous mutations in sequences of Mycobacterium tuberculosis GyrA and KatG genes  // Tuberculosis - 2012. - Vol.92. - Issue 4. - P. 333-344.

  5. Khrustalev V.V., Barkovsky E.V. A blueprint for a mutationist theory of replicative strand asymmetries formation  // Current Genomics - 2012. - Vol.13. - Issue 1. - P. 55-64.

  6. Khrustalev V.V., Barkovsky E.V. Percent of highly immunogenic amino acid residues forming B-cell epitopes is higher in homologous proteins encoded by GC-rich genes // Journal of Theoretical Biology – 2011. – Vol.282. – P.71-79.

  7. Khrustalev V.V., Barkovsky E.V. Unusual nucleotide content of Rubella virus genome as a consequence of biased RNA-editing: comparison with Alphaviruses // International Journal of Bioinformatics Research and Applications – 2011. – Vol.7. – Issue 1. – P.82-100.

  8. Khrustalev V.V., Barkovsky E.V. “Protoisochores” in certain archaeal species are formed by replication-associated mutational pressure // Biochimie. – 2011. – Vol.93. – Issue 2. – P.160-167.

  9.  Khrustalev V.V., Barkovsky E.V. The level of cytosine is usually much higher than the level of guanine in two-fold degenerated sites from third codon positions of genes from Simplex- and Varicelloviruses with G+C higher than 50% // Journal of Theoretical Biology. – 2010. – Vol.266. – Issue 1. – P.88-98.

  10.  Khrustalev V.V., Barkovsky E.V. The probability of nonsense mutation caused by replication-associated mutational pressure is much higher for bacterial genes from lagging than from leading strands // Genomics. – 2010. – Vol.96. – Issue 3. – P.173-180.

  11. Khrustalev V.V. Levels of HIV1 gp120 3D B-cell epitopes mutability and variability: searching for possible vaccine epitopes // Immunological Investigations. – 2010. – Vol.39. – Issue 6. – P.551-569.

  12. Khrustalev V.V., Barkovsky E.V. Study of completed archaeal genomes and proteomes: hypothesis of strong mutational AT pressure existed in their common predecessor // Genomics, Proteomics and Bioinformatics. – 2010. – Vol.8. – Issue 1. – P.22-32.

  13. Khrustalev V.V. Mutational pressure makes HIV1 gp120 linear B-cell epitopes shorter and may lead to their disappearance. // Molecular Immunology. – 2010. – Vol.47. – Issues 7-8. – P.1635-1639.

  14. Khrustalev V.V., Barkovsky E.V. Mutational pressure is a cause of inter- and intragenomic differences in GC-content of simplex and varicello viruses // Computational Biology and Chemistry. – 2009. – Vol.33. – Issue 4. – P.295-302.

  15. Khrustalev V.V. Can mutational GC-Pressure create new linear B-cell epitopes in Herpes Simplex virus type 1 glycoprotein B? // Immunological Investigations. – 2009. – Vol.38. – Issue 7. – P.613-623.

  16.  Barkovsky E.V., Khrustalev V.V. Inverse Correlation between the GC Content of Bacterial Genomes and Their Level of Preterminal Codon Usage // Molecular Genetics, Microbiology and Virology. – 2009. – Vol.24. – No.1. – P.17-23.

  17. Khrustalev V.V., Barkovsky E.V. Mutational Pressure in Genomes of Human a-Herpesviruses // Molecular Genetics, Microbiology and Virology. – 2008. – Vol.23. – No.2. – P.94-100.

  18. Khrustalev V.V., Barkovsky E.V. An in-silico study of alphaherpesviruses ICP0 genes: Positive selection or strong mutational GC-pressure? // IUBMB Life. – 2008. – Vol.60. – Issue 7. – P.456-460.

 


 

Òåçèñû

 

 

1.      Khrustalev V. V. , Lelevich S. V., Barkovsky E. V. Docking of ethanol to 3D models of human and rat muscle and liver phosphofructokinases // Acta Biochimica Polonica. – 2013. – Vol. 60. – S. 1. – P. 137.

2.      Khrustaleva T. A., Khrustalev V. V., Barkovsky E. V. Structural context around amino acid residues binding Mn+2 ions in bacterial proteins // Moscow Conference on Computational Molecular Biology (MCCMB'13): Proceedings. – 2013 – N. 124.

3.      Lelevich S. V., Khrustalev V. V., Barkovsky  E. V. Deep insights into the history of hexokinases evolution based on mutational pressure theory // Moscow Conference on Computational Molecular Biology (MCCMB'13): Proceedings. – 2013 – N. 125.

4.      Khrustalev V. V., Vasilevskaya A. E., Skripko S. M., Barkovsky E. V., Semizon P. A. Affinity purification of antibodies cross-reacting with peptide NQ21 corresponding to the less mutable HIV1 gp120 epitope // “HIV in European Region – Unity and Diversity”, Abstract Book, Tallinn, Estonia – AIDS 2011 – Tallinn, 2011. – P. 145.

5.      Khrustalev V. V., Barkovsky  E. V. The influence of directional mutational pressure on different characteristics of proteins from proteomes of Simplex- and Varicelloviruses // Book of Abstracts of the 2nd International Congress on Analytical Proteomics, Ourense, Spain – ICAP 2011 – Ourense, 2011. – P. 84.

6.      Khrustalev V. V., Vasilevskaya A. E., Skripko S. M., Barkovsky E. V. Peptide NQ21 corresponding to the HIV1 gp120 epitope with the most unique dipeptide composition shows cross-reactivity with human sera of HIV1-infected persons // Book of Abstracts of the 2nd International Congress on Analytical Proteomics, Ourense, Spain – ICAP 2011 – Ourense, 2011. – P. 190.

7.      Khrustalev V.V., Barkovsky E.V. APOBEC1 editing of HIV1 RNA often leads to the destruction of linear B-cell epitopes: case study of env gene region coding for gp120 protein // New Biotechnology. – 2010. – Vol.27. – Supplement 1. – P.S20.

8.      Arjomanzadegan M., Titov L.P., Barkovsky E.V., Khrustalev V.V. Study of GC content in regulatory gene whiB7 from Belarusian resistant isolates of M. tuberculosis. // The International Journal of Tuberculosis and Lung Disease. – 2010. – Vol. 14. – N.11. – S.2 – P.338.

9.      Khrustalev V.V., Barkovsky E.V., Zadorozniy D.Y. Genotypic method for checking and predicting acyclovir-resistance on the level of human alphaherpesviruses thymidine kinases // FEBS Journal. – 2009. – Vol.276. – Supplement 1. – P.317.

10.  Khrustalev V.V., Barkovsky E.V. Common predecessor’s effect in archaeal genomes and proteomes // Proceedings of the 4-th International Moscow Conference on Computational Molecular Biology “MCCMB’09”. Moscow, Russia. – 2009. – P.163-164.

11.  Khrustalev V.V., Barkovsky E.V., Zadorozniy D.Y. Computer algorithms for checking the acyclovir-resistance of herpes simplex viruses on the molecular level of the thymidine kinase // Acta Biochimica Polonica. – 2008. – Vol.55. – Supplement 4. – P.67.

12.  Khrustalev V.V., Barkovsky E.V. Levels of CpG and GpC dinucleotides in coding districts of archaeal genomes // Computational Phylogenetics and Molecular Systematics “CPMS’ 2007”. Conference proceedings. Moscow: KMK Scientific Press Ltd. – 2007. – P.354-357.

 

 

Íà ãëàâíóþ ñòðàíèöó